Eliza Murphy

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RESEARCH PROJECT

Tumor micorenvironment in melanoma brain metastasis 

An estimated 20-40% of patients with solid cancers develop brain metastases, which most commonly originate from lung, breast, and skin cancers. Brain metastases yield a poor prognosis and vastly reduced quality of life and commonly recur after tumor removal surgery. The Siegel Lab has previously characterized two growth patterns of melanoma brain metastases: minimally invasive and highly invasive, in which highly invasive metastases are more integrated into the tissue and much more likely to recur after resection. I work with Caitlyn Mourcos on her PhD project, which aims to better understand the mechanisms that drive the highly invasive melanoma brain metastasis phenotype and identify targets for future therapies.  


CONTACT INFO

Rosalind and Morris Goodman Cancer Research Centre - McGill University
1160 Pine Ave. West (Room 508)
Montreal, Quebec (Canada)
H3A 1A3
T. 514.398.8889
F. 514.398.6769

Email